Multiple Sclerosis

Multiple Sclerosis and C60

C60 buckyballs are said to be latent but powerful anti-aging agents. While there hasn’t been much in terms of extensive studies and research on this topic, the possibility of C60’s anti-oxidant abilities is quite high — so much so that Dr. Michael Gozin from TAU’s School of Chemistry is attempting to create a drug for Multiple Sclerosiswith buckyballs as the delivery platform.

Here is some studies that researchers have done on C60 and Alzheimer’s,as more studies come up we will add them to this page.

 

Fullerene to treat multiple sclerosis

Until now, buckyball-derived therapeutics have not been used in medicine. But the TAU and Harvard teams believe that they may resolve issues related to this nanomaterial development, and are seeking to commercialize their patented invention. If successful, the TAU-Harvard collaboration could provide new hope to millions of MS sufferers, and would make Bucky himself proud.

https://www.nanowerk.com/news/newsid=9716.php

 

Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis

Axonal degeneration is an important determinant of progressive neurological disability in multiple sclerosis (MS).  In this study we employed a model in which myelin-oligodendrocyte glycoprotein–immunized (MOG-immunized) NOD mice develop chronic progressive EAE to test a C60-fullerene derivative as what we believe to be a novel therapeutic approach to confer neuroprotection and reduce disease progression.

https://www.jci.org/articles/view/33464

C60 Fullerenes: The Medical Application of Buckyballs

C60 fullerenes, also known as buckyballs, have recently come to light as substance with overwhelming potential. Aside from being a possible contender collagen, stem cells, and other big-name players in the anti-aging industry, C60buckyballs have also presented promising latent abilities in cell growth and regeneration, mitochondrial function, and practical building applications. In this article, we discuss the untouched potential of C60 buckyballs in the field of science and medicine.

https://medium.com/@bestcarbonplus60/c60-fullerenes-the-medical-application-of-buckyballs-54bd28da2107

 

Application of fullerenes in nanomedicine: an update.

Fullerenes are carbon spheres presently being pursued globally for a wide range of applications in nanomedicine. These molecules have unique electronic properties that make them attractive candidates for diagnostic, therapeutic and theranostic applications.

https://www.ncbi.nlm.nih.gov/pubmed/23837857

 

 

Fullerene–biomolecule conjugates and their biomedicinal applications

The fullerene derivative was demonstrated to reverse the axonal loss and disability in a mouse model of progressive multiple sclerosis. In vitro assays showed that it could protect neurons from oxidative and glutamate-induced injury and restored glutamine synthetase and glutamate transporter expression in astrocytes after suffering inflammatory-related insults.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872219/