Alzheimer

C60 and Alzheimer

C60 has been documented in research studies to be 10-100x more effective as an antioxidant than vitamin E. In a study conducted on Alzheimer rodents treated with C60, the rodents developed Alzheimer’s later in life, and as a result, they lived longer.

Here is some studies that researchers have done on C60 and Alzheimer’s,as more studies come up we will add them to this page.

In 2012 researchers have shown, using computer simulations, that C60 is able to destabilise the structure of the amyloid-β protein and prevent the formation of the amyloid plaques. The hope is for C60 slowing or reversing Alzheimer’s disease. Another group were able, using electron microscopy, to photograph the C60 molecules preventing the formation of amyloid fibrils and so C60 might prevent Alzheimer’s disease. They also showed that a polycarboxyl derivative of C60 destroyed mature amyloid fibrils of muscle protein and prevented formation of new fibrils [2]. A further studied showed C60 had neuroprotective effects on the brain [3]. In studies on a strain of mice which develops dementia, showed those given C60 were able to remember their way round a maize whilst those not given it lost their spatial memory with age. The mice given C60 also had increased their life duration [4]

Amyloid-β fibril disruption by C60-molecular guidance for rational drug design.

https://www.ncbi.nlm.nih.gov/pubmed/22596218 

Beta-amyloid peptides are protein fragments that are naturally found throughout the body. Large clusters of beta-amyloid are referred to as plaques, and are seen in the brains of people with diseases such as Alzheimer’s or multiple sclerosis. Although the exact mechanisms remain unclear, beta-amyloid aggregates are generally thought to be detrimental to brain function.

Fullerenes C60, antiamyloid action, the brain, and cognitive processes

https://www.researchgate.net/publication/225366871_Fullerenes_C60_antiamyloid_action_the_brain_and_cognitive_processes

Neuroprotective effects of hydrated fullerene C60: cortical and hippocampal EEG interplay in an amyloid-infused rat model of Alzheimer’s disease.

https://www.ncbi.nlm.nih.gov/pubmed/25589720

A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice

https://www.semanticscholar.org/paper/A-carboxyfullerene-SOD-mimetic-improves-cognition-Quick-Ali/1df9c9f9dc6a5139411fd46a10a416be5a5397d7 

Drinking Ukrainian buckyballs to treat Alzheimer’s Disease

https://www.pnas.org/content/94/17/9434.full 

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